Blar i forfatter "Wang, Lu"

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    • Comparative validation of multi-instance instrument segmentation in endoscopy: Results of the ROBUST-MIS 2019 challenge 

      Ross, Tobias; Reinke, Annika; M. Full, Peter; Wagner, Martin; Kenngott, Hannes; Apitz, Martin; Hempe, Hellena; Mindroc Filimon, Diana; Scholz, Patrick; Tran, Thuy Nuong; Bruno, Pierangela; Arbeláez, Pablo; Bian, Gui-Bin; Bodenstedt, Sebastian; Lindström Bolmgren, Jon; Bravo-Sánchez, Laura; Chen, Hua-Bin; González, Cristina; Guo, Dong; Halvorsen, Pål; Heng, Pheng-Ann; Hosgor, Enes; Hou, Zeng-Guang; Isensee, Fabian; Jha, Debesh; Jiang, Tingting; Jin, Yueming; Kirtac, Kadir; Kletz, Sabrina; Leger, Stefan; Li, Zhixuan; H. Maier-Hein, Klaus; Ni, Zhen-Liang; Riegler, Michael; Schoeffmann, Klaus; Shi, Ruohua; Speidel, Stefanie; Stenzel, Michael; Twick, Isabell; Wang, Gutai; Wang, Jiacheng; Wang, Liansheng; Wang, Lu; Zhang, Yujie; Zhou, Yan-Jie; Zhu, Lei; Wiesenfarth, Manuel; Kopp-Schneider, Annette; P. Müller-Stich, Beat; Maier-Hein, Lena (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-28)
      Intraoperative tracking of laparoscopic instruments is often a prerequisite for computer and roboticassisted interventions. While numerous methods for detecting, segmenting and tracking of medical instruments based on endoscopic video images have been proposed in the literature, key limitations remain to be addressed: Firstly, robustness, that is, the reliable performance of state-of-the-art methods ...

    • Genetically predicted cortisol levels and risk of venous thromboembolism 

      Allarai, Elias; Lee, Wei-Hsuan; Burgess, Stephen; Larsson, Susanna C.; Lindstrom, Sara; Wang, Lu; Smith, Erin N.; Gordon, William; Van Hylckama Vlieg, Astrid; De Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Brumpton, Ben Michael; Chasman, Daniel I.; Suchon, Pierre; Chen, Ming-Huei; Turman, Constance; Germain, Marine; Wiggins, Kerri L.; Macdonald, James; Brækkan, Sigrid Kufaas; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rabecca D.; Nielsen, Jonas B; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; Frazer, Kelly A.; Mccauley, Bryan M.; Taylor, Kent; Pankow, James S.; Reiner, Alexander P.; Gabrielsen, Maiken Elvestad; Deleuze, Jean-Francois; O'Donnell, Chris J.; Kim, Jihye; Mcknight, Barbara; Kraft, Peter; Hansen, John Bjarne; Rosendaal, Frits Richard; Heit, John A.; Psaty, Bruce M.; Tang, Weihong; Kooperberg, Charles; Hveem, Kristian; Ridker, Paul M.; Morange, Pierre-Emmanuel; Johnson, Andrew D.; Kabrhel, Christopher; Alexandretrégouët, David; Smith, Nicholas L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Introduction - In observational studies, venous thromboembolism (VTE) has been associated with Cushing’s syndrome and with persistent mental stress, two conditions associated with higher cortisol levels. However, it remains unknown whether high cortisol levels within the usual range are causally associated with VTE risk. We aimed to assess the association between plasma cortisol levels and VTE risk ...

    • SIRT1 - a new mammalian substrate of nuclear autophagy 

      Wang, Lu; Xu, Caiyue; Johansen, Terje; Berger, Shelley L.; Dou, Zhixun (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-20)
      Macroautophagic/autophagic degradation of nuclear components (or nuclear autophagy) is a poorly understood area in autophagy research. We previously reported the nuclear lamina protein LMNB1 (lamin B1) as a nuclear autophagy substrate in primary human cells, stimulating the investigation of nuclear autophagy in the mammalian system. We recently reported the sirtuin protein SIRT1 as a new selective ...

    • SIRT1 is downregulated by autophagy in senescence and ageing 

      Xu, Caiyue; Wang, Lu; Fozouni, Parinaz; Evjen, Gry; Chandra, Vemika; Jiang, Jing; Lu, Congcong; Nicastri, Michael; Bretz, Corey; Winkler, Jeffrey D.; Amaravadi, Ravi; Garcia, Benjamin A.; Adams, Peter D.; Ott, Melanie; Tong, Wei; Johansen, Terje; Dou, Zhixun; Berger, Shelley L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-28)
      SIRT1 (Sir2) is an NAD<sup>+</sup>-dependent deacetylase that plays critical roles in a broad range of biological events, including metabolism, the immune response and ageing<sup>1,2,3,4,5</sup>. Although there is strong interest in stimulating SIRT1 catalytic activity, the homeostasis of SIRT1 at the protein level is poorly understood. Here we report that macroautophagy (hereafter referred to as ...

    • Traditional Chinese Medicine in Cancer Care: A Review of Case Series Published in the Chinese Literature 

      Yang, Goyan; Li, Xun; Li, Xiaoli; Wang, Lu; Li, Jia; Song, Xue; Chen, Jizhong; Guo, Yu; Sun, Xiaoxuan; Wang, Shana; Zhang, Zhiqi; Zhou, Xiaoyun; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-31)
      Traditional Chinese medicine (TCM) has been widely used in cancer in China. Case series report a series of cases exposed to a certain intervention. To understand the current situation of case series of TCM for cancer, we performed this review. We included case series of cancer patients treated with TCM therapy. Electronic searches were conducted in four main Chinese databases until February 2011. ...